OB/Gyns tend to overcompensate on preventatives. For me this was a big shock, I’ve not had any blood transfusions and have had 2 very healthy boys. If the King had not had a “k” gene to give them, they would have died in utero or a few hours after their birth like their poor siblings did. Moreover if your wife had a C-section then she has had major abdominal surgery and all kinds of transfer can happen. About 500 members… So helpful!!y. However, a wise doctor would panic and NOT push the issue … just in case. As far as I know (and remember I’m not an MD so if your doctor says otherwise listen to him/her!) It could be prevented if they would just screen. Well I am 13 weeks pregnant now, and I just was informed by my doctor that I have the anti-kell antigan. Stress can also hurt you and the baby. I have been searching all over the net to answer my question but only find general references to “testing” but no explanation of how one goes about testing to see if kell or other similar things are the cause of recurrent pregnancy losses between two partners. Am I at risk for anything because of this antigen?? A Kell positive man can cause serious problems for his reproductive partners after the first pregnancy, because a Kell negative mother’s body will develop a Kell alloimmunization — which means that her body would attack a Kell positive fetus as “foreign” and the result is fetal or neonatal death. Beings you did NOT mention a transfusion it is likely your husband is a carrier. If you plan to have more children, you might want to get your husband to go for a blood test to see if he has Kell+ blood. After giving blood twice I recieved a letter letting me know I was A+ kell. You can get the boys tested now and then they can warn their wife/partner if and when pregnancy is a possibility. Egg. I was born 3 weeks early, with jaundice much more severe than my sister or brother had. The Kell antigens are K, k, Kp a, Kp b, Js a and Js b. The good news is that your husband is EXTREMELY likely to have a non-Kell gene as well as a Kell gene to give an embryo. I did indeed *almost* die in the womb, and the Obstetrician said I probably wouldn’t live very long after birth at the rate things were going. Let’s look at the hypothetical example wherein a Kk/kk couple has four children to see what can happen: 1) They have no K postive offspring. **Please note, I am not a medical professional, so please forgive any errant use of medical terms in the following**. i am around 29/30 weeks along in my pregnancy. Which means ONE (which one is anyone’s guess and it would take bloodtyping to find out) of your former pregnancies had a Kell positive fetus. Thank Goodness all is ok, but now I don’t think I can donate Blood anymore which is sad as I am 90% of the population is Kell negative. Their children have the potential genotypes of: We know two things from these squares and the fact Kell positive blood is rare. If you test positive for COVID-19, you need to isolate yourself from other people. The Kell antigen system (or the Kell-Cellano system) was named after the family of the antibody producer Mrs. Kellacher. I hope their next fetus is Kell- or that the Ob/Gyns can do more to help and keep the fetus safe until old enough to be born. I’m pretty sure at least a few of the generations had multiple siblings of both genders. This is in addition to the ABO blood groups that most people know about. Your daughter will not be troubled by Kell+ because her body will not attack the fetus either with or without Kell. I hope he is not Kell positive, but I have to tell you that yes he could be. The antibodies are usually made after a blood transfusion.. It can be used in many aspects, referring to: what, how much or how high one gets. I was thinking maybe my grandson’s mother should get tested just in case. However, your should be safe on the Kell front. i found out about 2 months ago that i have the kell anti-body. Debbie , New York. So as I understand all my other babies were kell negative and if this baby is kell postive my body will give this baby a chance ? Your body won’t attack a Kell+ baby because it is the SAME and it won’t attack a Kell- baby because there is no antigen there to set it off. I am so sorry. There are apparently quite a few antigenic things that can be running around on the surface of your red blood cells. Now I have anti-kell showing up on my blood test. They’ll need to get tested, because your daughters will have no reproductive issues, if your son has the Kk then his reproductive partner’s Ob/Gyn will need to know to keep a close eye on her pregnancies. My wife is pregnant with our fourth child and has had three prior C Sections. Random chance works like that. If your husband is Kk then the babies could have the Kell antigen. Thus it is critical this is passed off to a dr who specializes in this condition. What happens if I don’t pass it on to the fetus and I’m positive but fetus is negative? If your next baby has no Kell antigen, then it will be fine. (Well, it used to be like that before modern medical treatments that will keep a Kell positive fetus alive inside a Kell negative mother. A very simplified version of how a dominate gene (especially one that is harmful under certain conditions) can wind up being in only a small minority of a population. And the most common for Europeans and Africans was the K-k+. I just have a biology degree and study doctors. Oh ya, and meant to say that the blood transfusion is how I got the kell. If two couples, let’s name them Ted (BB) & Alice (bb) and Bob (bb) & Jane (Bb), have children who marry each other then it is possible that all their grandchildren can have blue eyes in spite of the fact that two grandparents have the dominate brown-eyed gene. I am not a medical doctor, but I will give you all the information I have. If it is a first pregnancy, then the mother’s body will not attack the fetus even if it is Kell positive. Unless one of the offspring reproduces with a Kell positive partner (which is a less than 10% chance) no grandchildren will be Kell positive, and so on forevermore. I am wondering, can two positive kell people have children together? Virtually everyone is Kell positive. Okay, the GOOD news is that as a K+ woman your pregnancies will never be effected. Things I know — it is rare, but anti-K antibodies can show up in a first pregnancy, so you aren’t alone. Any ideas on where the pos K people are from?? For one thing, people who are homozygous (KK) for Kell are rare. I am have developed anit kell anit bodies I think for a blood transfusion I had way back in 2003 .my question is I have 7 children all from the same dad If you need more support with Kell… Look up the “ISO moms” group on Facebook. I’m an anthropologist, and maybe a specialist in genetic transmission could help you. If you test positive, know what protective steps to take to prevent others from getting sick. The funny thing about a Kell positive blood type is that the Kell antigen is passed on by a dominate gene, but even though it is dominate it is rare; less than 10% of the people in the UK have it. Anti-K antibodies, for example, bind to the 'Kell antigen' on red blood cells. No trouble there either and apparently no prophylaxis or special treatments given to my mother (I asked). Forgot to post this; my apologies for the delay). So of you are Kk, then are you positive or negative? I am anti-k (lowercase) so it is kind of like a cousin to Kell. The Kell blood type system is highly polymorphic, meaning that there are many different alleles (alternative forms of a gene) - about 25! BEST WISHES!!!! Is Kell only spread by the men? After this I was informed that I could not only not donate blood but could not donate plasma, be a organ donor etc. Did her Ob/Gyn not test for Kell antibodies in her blood after the third miscarriage? However, if all four children are boys then the Kell gene is much less likely to turn up in the grandchildren, because every pregnancy after the FIRST one will only survive if it is Kell negative (kk). Le système Rhésus est un système complexe qui comporte plusieurs antigènes dont le plus important pour la transfusion est l’antigène D. Sur les globules rouges des sujets dits Rhésus négatifs l’antigène D n’est pas présent alors qu’il l’est chez les sujets Rhésus positif. It has NOTHING to do if they are KK, or kk, or Kk. After losing two pregnancies, I was blessed with three healthy babies in a row. help Looking for a shoulder to cry on while I go through this process. 1. It will be a normal pregnancy, like your last one. I am in the same boat as this woman above. I will not be having any more children, but am concerned that it may be an issue for them when they have children. I am terrified but there are no support groups for Mom’s struggling with this since it is so rare. I would encourage you if you are ever hospitalized to be sure that you tell your nurses and doctors that you have an antibody. At one point they thought I might be twins, one dead, one alive, because the amnio said my environment was toxic, but my sonogram said my heart was still beating. i have some questions about the kell gene and the risks that it might causes of a baby. The baby could miscarry or die of hemolytic disease of the newborn if your wife unknowingly has the anti-Kell antigens and steps aren’t taken. Does pregnancy always have to end in trouble when Kell antigens are involved? Kell positive boys can have problems with reproducing, tho. If you only have two or three children, you may never even have a Kell-effected pregnancy, because you might have the good luck that the babies never get your husband’s genes. O positive blood type is about 37% in Caucasians, 47% in African American, 53% in Hispanic, and 39% in Asian. I’m 34 years old. Thanks so much for getting back to me.my titer level is 1.8 which is pretty high. I hope I explained why your last healthy baby could have been unknown Kell positive adequately? I am sorry to say that I am not a doctor and cannot help you with future blood type issues, but the good news is you might not need to worry at all: http://www.sciencealert.com/artificial-blood-could-be-used-in-trial-transfusions-by-2016 What I can tell you that as long as any future children are Kell negative it won’t cause any problems in pregnancy. I’m trying to understand what it means that I’m K+k+. I love my wife and my kids, regardless of their origin. However, I am not able to get a clear answer even from my infertility specialist, who said he would have to “look it up” (then promptly forgot/ignored my question). Detection of viral RNA does not necessarily mean that a person is infectious and able to transmit the virus to another person. Any advice? Because I don’t really see the concern as you are R h positve. I’m currently 33 weeks pregnant. If the girl is either Kell positive or negative, it shouldn’t be a problem for her. Like the punnett square shows, I have a 50% chance of passing it on to baby. I suggest you get one of the boys (other than the first born) and have him tested for Kell antigens. They said the last three weeks of pregnancy would almost certainly kill me. Also, if a baby is cellano-negative (which it might very well be and indeed probably is) then the body won’t attack the fetus; your antigens won’t “see” anything there to attack. To clarify what you seem to misunderstand, even blood bankers are guilty of calling “K’ the “Kell” antigen, and “k” the “cellano” antigen. I would recommend retesting Dad because a false negative is the most likely explanation. If you do get a Kell positive fetus then there ARE things the doctor can do to save the pregnancy. So no, it is not rare. In Blood Will Tell I talked about the theory that Henry VIII had a Kell positive blood type, but in my quest to prevent innocent readers from slipping into an over-science coma I didn’t go into deep detail about it. Dominate browns can easily be hiding secret blue genes (insert blue jean joke here) but the brown B is gone once the recessive have the field. Or maybe none of them will be. I absolutely LOVE your historical research, as a geneology nerd myself it makes me happy. Once she’s exposed, she develops anti-Kell antibodies, which can attack and destroy Kell-positive red blood cells. I am so very, very sorry for the loss of your triplets. My second child, my son, had mild haemolytic disease of the newborn. If two of your sons are Kell positive, I strongly suggest testing everyone. Also, multiple miscarriages could have been because of a physiological issue in the mother, as well. Do you mean you have Kell antibody. Thanks. He is 100% the father as well. I’m already on weekly appointments. My doctor was under the impression all they would do was an early delivery starting at 25 wks. Would my body make the anti-kell show up even if daddy is negative? If you are making Kell antibodies (reacting to fetal Kell antigens) then you are Kell negative and had jaundice because your blood type was different from your mum’s. This means approximately 35.7% of the population has an A positive blood. This seemed to surprise the doctor who offered no explanation as to why in our visit. I am sorry that this got trapped in my comment filter and I just saw it. Okay, let’s call the Kell positive allele “K” and the Kell negative gene “k”. This exact scenario actually happened to me. Wait another 3 weeks…. I contracted the Kell antibody because of a blood transfusion I had after my 1st pregnancy which was a c-sec. Some people have it; some don’t. I am sorry, but I am not a doctor, so I may be no help at all. 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